– Genetic Testing costs Rs.10,500 /- Only*
Genetic Testing
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Did you know?
Inherited gene mutation is responsible to contribute to about 10% of breast cancers.
Who should consider for genetic testing for cancer risk?
The features of a person’s personal or family medical history that, particularly in combination, may suggest a hereditary cancer syndrome include:
1. Cancer was diagnosed at an unusually young age
2. Several different types of cancer occurred in the same person
3. Cancer in both organs in a set of paired organs, such as both kidneys or both breasts
4. Several first-degree relatives (the parents, siblings, or children of an individual) have the same type of cancer (for example, a mother, daughter, and sisters with breast cancer); family members with breast or ovarian cancer; family members with colon cancer and endometrial cancer
5. Unusual cases of a specific cancer type (for example, breast cancer in a man)
6. The presence of birth defects that are known to be associated with inherited cancer syndromes, such as certain noncancerous (benign) skin growths and skeletal abnormalities associated with neurofibromatosis type 1.
7. Being a member of a racial or ethnic group that is known to have an increased risk of having a certain inherited cancer susceptibility syndrome and having one or more of the above features as well
8. Several family members with cancer
“My Doctor estimated that I had an 87% risk of Breast Cancer and a 50% risk of Ovarian Cancer.”
– Angelina Jolie
BRCA mutations are responsible for the majority of hereditary breast and ovarian cancers.
1. BRCA1 and BRCA2 are human genes that produce tumor suppressor proteins.
2. These proteins help in repairing damaged DNA and, therefore, plays a crucial role in ensuring the stability of the cell’s genetic material.
3. When either of these genes is mutated, or altered, such that its protein product is not made or does not function correctly, DNA damage may not be repaired properly.
4. As a result, cells are more likely to develop additional genetic alterations that can lead to cancer or related tumors growth.
5. A harmful BRCA1 or BRCA2 mutation can be inherited from a person’s mother or father.
6. Genetic Testing can be done to identify if Inherited BRCA gene mutation or any other oncogene panel responsible for Breast cancer.
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Frequently Asked Questions (FAQ)
What is the cost of Genetic Testing?
What is included in the Cost?
– Genetic Testing
– Home Sample Collection
– Free Counselling
– e-Consultation
How is genetic testing done?
– Genetic Testing is done on a small sample of bodily fluid or tissue—usually blood.
What do the results of genetic testing mean?
– Positive result – Confirm that the cancer was likely due to an inherited genetic variant
– Negative result- Does not have inherited genetic variant present in their family
– Variant of uncertain significance – A change that has not been previously associated with cancer
– Benign variant – Common in the general population among people without cancer
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